abstract：PURPOSE:Adjuvant chemotherapy with oxaliplatin combined with a fluoropyrimidine derivative is widely accepted as standard therapy for patients with stage III colon cancer, since few clinical data are available for Japanese patients. The FACOS trial investigated the tolerability of modified FOLFOX6 (mFOLFOX6) and XELOX ...

journal_title：International journal of colorectal disease

authors： Kosugi C,Koda K,Ishibashi K,Yoshimatsu K,Tanaka S,Kato R,Kato H,Oya M,Narushima K,Mori M,Shuto K,Ishida H

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Lynch syndrome (LS) is associated with a high risk of colorectal cancer (CRC). The aim of this study was to assess the cumulative risk for the development of colorectal adenomas or carcinomas in a LS CRC surveillance program and to audit the quality of the endoscopic procedures. METHODS:We evaluated 147 asympt...

journal_title：International journal of colorectal disease

authors： Vale Rodrigues R,Claro I,Lage P,Rosa I,Ferreira S,Pereira da Silva J,Dias Pereira A

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To identify factors associated with timing of stoma reversal after rectal cancer surgery in a large Swedish register-based cohort. METHODS:Three thousand five hundred sixty-four patients with rectal cancer who received a protective stoma during surgery in 2007-2013 were identified in the Swedish colorectal can...

journal_title：International journal of colorectal disease

authors： Gustafsson CP,Gunnarsson U,Dahlstrand U,Lindforss U

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:Compared with the open approach, laparoscopic total mesorectal excision (TME) achieves faster patient recovery, reduces morbidity rates, and shortens hospital stay. However, in laparoscopic low anterior resection (L-LAR), conversion to open surgery is required in almost 20% of cases. Transanal TME (Ta-TME) comb...

journal_title：International journal of colorectal disease

authors： Serra-Aracil X,Zárate A,Mora L,Serra-Pla S,Pallisera A,Bonfill J,Bargalló J,Pando A,Delgado S,Balleteros E,Pericay C

更新日期：2018-05-01 00:00:00

abstract：AIMS:Percutaneous tibial nerve stimulation (PTNS) and sacral nerve stimulation (SNS) are both second-line treatments for faecal incontinence (FI). To compare the clinical outcomes and effectiveness of SNS versus PTNS for treating FI in adults. METHOD:A literature search of MEDLINE, Embase, Science Citation Index Expan...

journal_title：International journal of colorectal disease

authors： Simillis C,Lal N,Qiu S,Kontovounisios C,Rasheed S,Tan E,Tekkis PP

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To analyze the results of abdominoperineal excisions (APE) for locally advanced rectal cancer at our institution before and after the adoption of extralevator abdominoperineal excision (ELAPE) with a special reference to long-term survival. METHODS:A retrospective cohort study conducted in a tertiary referral ...

journal_title：International journal of colorectal disease

authors： Carpelan A,Karvonen J,Varpe P,Rantala A,Kaljonen A,Grönroos J,Huhtinen H

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Anastomotic leakage after low anterior resection for rectal cancer is a critical problem. Many risk factors have been suggested and surgical techniques have improved, but anastomotic leakage remains a major postoperative challenge. This study sought to create a nomogram for precise prediction of anastomotic lea...

journal_title：International journal of colorectal disease

authors： Hoshino N,Hida K,Sakai Y,Osada S,Idani H,Sato T,Takii Y,Bando H,Shiomi A,Saito N

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:It is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD p...

journal_title：International journal of colorectal disease

authors： Brandlhuber M,Genzinger C,Brandlhuber B,Sommer WH,Müller MH,Kreis ME

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Malignant bowel obstruction is a complication of colorectal carcinoma or metastasis from other carcinoma, and it causes significant damage on the condition of elderly patients; however, the self-expandable metallic stents (SEMSs) have been effectively used either for palliation or for bridging to the surgical p...

journal_title：International journal of colorectal disease

authors： Imai M,Kamimura K,Takahashi Y,Sato T,Isokawa O,Maruyama M,Kobayashi T,Hayashi K,Terai S

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Diverticulosis and redundant colon are colonic conditions for which underlying pathophysiology, management and prevention are poorly understood. Historical papers suggest an inverse relationship between these two conditions. However, no further attempt has been made to validate this relationship. This study ...

journal_title：International journal of colorectal disease

authors： Cuda T,Gunnarsson R,de Costa A

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to identify the size criteria of lateral lymph node metastasis in lower rectal cancer both in patients who underwent preoperative CRT and those who did not. METHODS:This study enrolled 150 patients who underwent resection for primary lower rectal adenocarcinoma with lateral lymph ...

journal_title：International journal of colorectal disease

authors： Yamaoka Y,Kinugasa Y,Shiomi A,Yamaguchi T,Kagawa H,Yamakawa Y,Numata M,Furutani A

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:Adenoma detection in colorectal cancer survivors is poorly characterised with insufficient evidence to inform frequency of surveillance schedule. The aim of this study was to examine adenoma incidence and recurrence in patients who have undergone colorectal cancer resection with curative intent. Survival outcom...

journal_title：International journal of colorectal disease

authors： Patel A,Williams N,Parsons N,Ali O,Peters F,Ranat R,Shah J,Spector E,Arasaradnam RP

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Perianal fistulising Crohn's disease (PFCD) affects a third of Crohn's disease patients and represents a disabling phenotype with poor outcome. The anti-tumour necrosis factor alpha (TNF) therapies have been shown to maintain clinical remission in a third of patients after 1 year of treatment. Maintenance th...

journal_title：International journal of colorectal disease

authors： Adegbola SO,Sahnan K,Tozer PJ,Phillips RK,Faiz OD,Warusavitarne J,Hart A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:In preoperative blood management of colorectal cancer patients, intravenous iron therapy is increasingly used to treat anaemia and prevent red blood cell transfusions. However, while iron deficiency is the most common cause of anaemia, little is known about the prevalence and namely type of iron deficiency i...

journal_title：International journal of colorectal disease

authors： Wilson MJ,Dekker JWT,Harlaar JJ,Jeekel J,Schipperus M,Zwaginga JJ

更新日期：2017-11-01 00:00:00

abstract：AIM:The aim of this study was to analyze the results of nonoperative management of patients with perforated acute diverticulitis with extraluminal air and to identify risk factors that may lead to failure and necessity of surgery. METHODS:Methods included observational retrospective cohort study of patients between 20...

journal_title：International journal of colorectal disease

authors： Titos-García A,Aranda-Narváez JM,Romacho-López L,González-Sánchez AJ,Cabrera-Serna I,Santoyo-Santoyo J

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:TNF blockers are approved for intravenous or subcutaneous systemic therapy of many chronic inflammatory diseases. As it is not possible to achieve a sufficient local clinical improvement through systemic therapy in every patient, diverse approaches of topical therapy using TNF blockers have been investigated in...

journal_title：International journal of colorectal disease

authors： Teich N,Wallstabe I,Schiefke I

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:Several studies demonstrate an increased prevalence and concordance of inflammatory bowel disease among the relatives of patients. Other studies suggest that genetic influence is over-estimated. The aims of this study are to evaluate the phenotypic expression and the treatment requirements in familial inflammat...

journal_title：International journal of colorectal disease

authors： Ballester MP,Martí D,Tosca J,Bosca-Watts MM,Sanahuja A,Navarro P,Pascual I,Antón R,Mora F,Mínguez M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Diversion colitis (DC) seems to be common in stoma patients, and the restoration of the continuity of the digestive tract is crucial for relief from the inflammatory process. No prospective studies of the late effects of DC on the lower gastrointestinal (GI) tract mucosa and the clinical condition of patient...

journal_title：International journal of colorectal disease

authors： Szczepkowski M,Banasiewicz T,Kobus A

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS:Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 we...

journal_title：International journal of colorectal disease

authors： Gu J,Stocchi L,Ashburn J,Remzi FH

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Anastomotic leak (AL) in colorectal surgery leads to significant morbidity, mortality and poorer oncological outcomes. Diagnosis of AL is frequently delayed as current methods of detection are not 100% sensitive or specific. 'Biomarkers', such as cytokines and markers of ischaemia, from the milieu of the anasto...

journal_title：International journal of colorectal disease

authors： Wright EC,Connolly P,Vella M,Moug S

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:First degree relatives (FDR) of colorectal cancer (CRC) patients are at increased risk of CRC compared to the general population. However, screening colonoscopy rates amongst the FDRs remain dismal. The aim of the study was to explore the various issues amongst the patients and their FDR precluding their a...

journal_title：International journal of colorectal disease

authors： Tan KK,Lim TZ,Chan DKH,Chew E,Chow WM,Luo N,Wong ML,Koh GC

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:Rectal advancement flap is an accepted approach for treating complex fistula-in-ano. However, a diversity of technical modifications have been described. The aim of this study was to evaluate recurrence and fecal continence rates after performing rectal advancement flaps depending upon flap thickness (full-thic...

journal_title：International journal of colorectal disease

authors： Balciscueta Z,Uribe N,Balciscueta I,Andreu-Ballester JC,García-Granero E

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Symptomatic infection with Clostridium difficile is strongly linked to antibiotic use and rates are higher for colorectal surgery. In February 2015, trust policy for antibiotic prophylaxis of ileostomy reversal surgery was changed from three doses of metronidazole plus cefuroxime to single-dose metronidazole, i...

journal_title：International journal of colorectal disease

authors： Fernandes R,Robinson P,Rangarajan K,Scott S,Angco L

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:This study aims to evaluate pubovisceral muscle and anal sphincter defects in women with previous vaginal delivery and fecal incontinence and to correlate the findings with the severity of symptoms using the combined anorectal and endovaginal 3D ultrasonography with a new ultrasound scoring system. METHODS:Con...

journal_title：International journal of colorectal disease

authors： Murad-Regadas SM,da S Fernandes GO,Regadas FS,Rodrigues LV,Filho FS,Dealcanfreitas ID,da Silva Vilarinho A,da Cruz MM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:This paper aimed to study the long term follow-up of patients with primary rectal adenocarcinoma receiving neoadjuvant chemoradiotherapy who obtained a pathological complete response (pCR) and identify factors predicting complete response. METHODS:Retrospective review of notes, histology, pre-operative full bl...

journal_title：International journal of colorectal disease

authors： Runau F,Collins A,Fenech GA,Ford E,Dimitriou N,Chaudhri S,Yeung JM

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:We evaluated the efficacy of oral administration of a mixture of diosmin, coumarin glycosides, and Centella asiatica (Venoplant®) in preventing bleeding, pain, and thrombosis of internal and external hemorrhoids after stapled anopexy (SA). METHODS:SA was conducted in 182 patients with third-degree hemorrhoids....

journal_title：International journal of colorectal disease

authors： Schiano di Visconte M,Nicolì F,Del Giudice R,Cipolat Mis T

更新日期：2017-03-01 00:00:00

abstract：AIM:Rates of local recurrence (LR) after transanal endoscopic microsurgery (TEM) for rectal carcinoma vary; the reasons remain unclear. We analyzed LR after TEM for low-risk pT1 (G1/2/X, L0/X) rectal carcinoma to investigate the influence of completeness of resection and occult lymph node metastasis on risk of LR. MET...

journal_title：International journal of colorectal disease

authors： Junginger T,Goenner U,Hitzler M,Trinh TT,Heintz A,Roth W,Blettner M,Wollschlaeger D

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:The hypothesis in this study was that anaemia prior to surgery and perioperative red blood cell transfusion increases the risk for recurrence and overall mortality in patients with stages I-III colorectal cancer after abdominal resection with curative intent. METHODS:This is a Swedish single centre retrospecti...

journal_title：International journal of colorectal disease

authors： Mörner ME,Edgren G,Martling A,Gunnarsson U,Egenvall M

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Cancerous involvement of a ureter is sometimes encountered in pelvic surgery for malignancy. We usually perform transureteroureterostomy (TUU) in cases of unilateral lower ureteral cancerous involvement. We report the outcomes in patients treated with TUU in our institute. METHODS:We retrospectively reviewed t...

journal_title：International journal of colorectal disease

authors： Kawamura J,Tani M,Sumida K,Yazawa T,Kawasoe J,Yamamoto M,Harada H,Yamamoto H,Zaima M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Surgical site infection (SSI) continues to be a challenge in colorectal surgery. Over the years, various modalities have been used in an attempt to reduce SSI risk in elective colorectal surgery, which include mechanical bowel preparation before surgery, oral antibiotics and intravenous antibiotic prophylaxi...

journal_title：International journal of colorectal disease

authors： Koullouros M,Khan N,Aly EH

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Inflammatory bowel disease has been associated with neurological symptoms including restless legs syndrome. Here, we investigated the impact of restless legs syndrome in patients with inflammatory bowel disease on sleep, fatigue, mood, cognition, and quality of life. METHODS:Two groups of inflammatory bowel di...

journal_title：International journal of colorectal disease

authors： Schindlbeck KA,Becker J,Berger F,Mehl A,Rewitzer C,Geffe S,Koch PM,Preiß JC,Siegmund B,Maul J,Marzinzik F

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Ostomies are being placed in 35 % of patients after colorectal cancer surgery. As decision-making regarding colorectal surgery is challenging in the older patients, it is important to have insight in the potential impact due to ostomies. METHODS:An internet-based survey was sent to all members with register...

journal_title：International journal of colorectal disease

authors： Verweij NM,Hamaker ME,Zimmerman DD,van Loon YT,van den Bos F,Pronk A,Borel Rinkes IH,Schiphorst AH

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:The assessment of bowel habit is important in the management of patients with colorectal disease. There is not an ideal and practical bowel habit scoring system. The current scores have been designed only for a subclass of patients having a particular disorder. Furthemore, they are complex and time consuming. W...

journal_title：International journal of colorectal disease

authors： Zinicola R,Cracco N,Totaro A,Dalla Valle R,Pedrazzi G

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:There are no published data or guidelines on whether the same anti-tumor-necrosis factor (TNF) agents used preoperatively or different anti-TNF agents are preferable to treat postoperative recurrence. Our aim was to compare the efficacy of the consistent vs. switched anti-TNF approaches in patients with recurre...

journal_title：International journal of colorectal disease

authors： Li Y,Stocchi L,Rui Y,Remzi FH,Shen B

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to explore the effects of the fast-track surgery (FTS) program on inflammation and immunity in patients undergoing colorectal surgery. METHODS:From August 2014 to March 2015, a prospective and randomized controlled trial of 230 patients who underwent colorectal surgery was perf...

journal_title：International journal of colorectal disease

authors： Feng J,Li K,Li L,Wang X,Huang M,Yang J,Hu Y

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:ERAS (enhanced recovery after surgery) programs have proven to reduce morbidity and hospital stay in colorectal surgery. However, the feasibility of these programs in elderly patients has been questioned. The aim of this study is to assess the implementation and outcomes of an ERAS program for colorectal cancer...

journal_title：International journal of colorectal disease

authors： Gonzalez-Ayora S,Pastor C,Guadalajara H,Ramirez JM,Royo P,Redondo E,Arroyo A,Moya P,Garcia-Olmo D

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Functional constipation in children and adolescents is a common and invalidating condition. In a minority of patients, symptoms persist despite optimal conservative therapy. The aim of this study was to evaluate whether the short-term effects of sacral neuromodulation (SNM) in children and adolescents with cons...

journal_title：International journal of colorectal disease

authors： van der Wilt AA,van Wunnik BP,Sturkenboom R,Han-Geurts IJ,Melenhorst J,Benninga MA,Baeten CG,Breukink SO

更新日期：2016-08-01 00:00:00

abstract：AIM:To determine the relation between patient-related and histopathological factors, as well as the influence of national programs for diagnosing and treatment of colon cancer and a lymph node yield (LNY) ≥ 12. METHOD:An analysis was carried out of the LNY in a nationwide Danish cohort treated by curative resection of...

journal_title：International journal of colorectal disease

authors： Lykke J,Jess P,Roikjær O,Danish Colorectal Cancer Group.

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:The aim was to evaluate erectile and urinary function of male patients with rectal cancer treated by neoadjuvant (NA) chemoradiotherapy (CRT) or NA chemotherapy only. METHODS:In this prospective randomized trial (ClinicalTrials.gov NCT01211210; "FOWARC"), we included 102 men who received NA therapy for stage...

journal_title：International journal of colorectal disease

authors： Huang M,Lin J,Yu X,Chen S,Kang L,Deng Y,Zheng J,Luo Y,Wang L,Lan P,Wang J

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:Laparoscopy for colorectal cancer resection bares early post-operative advantages and results in equal oncologic long-term outcome. However, data on laparoscopic right hemi-colectomy is scarce. Aim of the present study was to analyze a well selected collective of patients with right-sided colon cancer treated o...

journal_title：International journal of colorectal disease

authors： Zimmermann M,Benecke C,Jung C,Hoffmann M,Nolde J,Schlöricke E,Bruch HP,Keck T,Laubert T

更新日期：2016-07-01 00:00:00